India's bowling line up failed to contain the Australian batsmen once again as the Kangaroos dominated the second half of the 1st innings.
After picking up four quick wickets, the Indian fielders were sent on a leather hunt as David Warner and Mitchell Marsh put up a solid partnership, with Warner reaching his century at a run rate of more than 100.
It was only after Warner was dismissed for 122 when the Indian bowlers pulled back. Ishant Sharma tricked the fiery Tasmanian with a slower delivery which brought Matthew Wade to the crease.
Wade set off on a quick cameo of 36 off 27 balls when Umesh Yadav took his wicket - forcing him to edge through to Mahendra Singh Dhoni behind the stumps.
But Yadav also gave away the most runs - 82 off his last 8 overs till the 48th over. Australia ended their innings on 330/7.
India will rely on the batting exploits of Virat Kohli, Shikhar Dhawan and Rohit Sharma once again to help them get over the line in the fifth and final One Day International, to avoid a series whitewash.